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KMID : 0613820060160010162
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Journal of Life Science
2006 Volume.16 No. 1 p.162 ~ p.167
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Effects of Eucalyptus and Geranium on Production of IL-2 and IL-4 in Mouse Splenocytes
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Cha Bong-Kyu
Jang Myung-Woong
Jeong Young-kee
Kim Kwang-Hyuk
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Abstract
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Aromatherpy is the controlled use of essential oils to promote health and well-being. In this work we have investigated the effect of eucalyptus and geranium on the production of interleukin-2 (IL-2) and interleukin-4 (IL-4). Mouse splenocytes were incubated with essential oils. The culture supernatants of mouse splenocytes exposed with these oils were harvested to assay IL-2 and IL-4 production. The quantitative changes of IL-2 in splenocytes culture supernatants after exposure with these oils were decreased at high doses, but increased at low doses. But its of IL-4 were increased generally at high doses of eucalyptus. In case of the exposure of geranium, its of IL-4 were dose-dependently increased. These kinds of essential oils showed the probability to improve IL-2- and IL-4-related immune responses at the optimum exposure.
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KEYWORD
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